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教授-研究员

刘勇
作者: 发布时间:2021-05-08 点击数:


基本信息

刘勇,男,博士,教授。主要从事生态毒理学方面研究。生态毒理学主要集中在两方面研究:1)宏观研究蓝藻水华产生藻毒素在湖泊内分布特点,微观开发新型技术实现对微囊藻毒素的的识别和检测,进一步研究其生态毒理性;2)与人体毒性分子的监测以及对人类健康影响评价,研究污染物环境毒理性。3 活性分子监测技术的研发及其毒理性研究。

电子邮箱:lycc2010@126.com

地址:云南省昆明市呈贡区大学城东外环南路(650500)。


成果简介

近年来,以第一作者和通讯作者在Water research (Nature index)Journal of Hazardous MaterialsAdvance scienceCoordin. Chem. Rev.等学术刊物上发表论文30余篇,其中JCR一区TOP,包括中科院一区SCI论文14篇。其中,IF>202, IF>106篇,IF>613篇。主持国家自然科学基金面上项目1项(在研),国家自然科学基金青年项目1项;云南省社会发展专项1项(在研),山东省自然科学基金项目1 ,云南省高层次人才项目1项(在研)。横向课题一项(在研),授权发明专利3项,成果转化一项。



【工作经历】

2020/12 -至今,云南大学bwin88必赢网址湖泊院 教授

2014/08 -2020/11 济南大学光功能材料与成像研究院 讲师 副教授


【教育背景】

2011/09 – 2014/06 山东大学  材料学博士

2008/09 – 2011/06 西北师范大学 化学 硕士

2004/09 – 2008/06 西安文理学院  化学 学士


【主持项目】

1. 云南省社会发展专项课题:基于湖泊治理与流域生态修复的核心关键技术研发; 项目编号:202103AC1000012021/04-2024/04; 在研,主持。

2. 国家自然科学基金面上项目:构建新型近红外荧光探针监测癌细胞和肿瘤内脱氧核糖核酸附近的生物硫醇;项目编号:51973082 2020/01 - 2023/12;在研,主持。

3. 国家自然科学基金青年项目,基于新型近红外荧光探针追踪癌细胞内核糖核酸(RNA)附近过氧化氢的动态变化研究,项目编号:51503077 2016/01-2018/12,主持,已结题。

4. 山东省自然科学基金, 构建新型近红外荧光探针追踪癌细胞内线粒体附近过氧化氢动态变化的研究,项目编号:ZR2015PE0012015/07-2016/12, 主持,已结题。

5. 横向课题,具有应用价值荧光技术研发2022.4-2025.12,经费:70万,主持,在研。

6. 校级博士基金,基于咔唑类双光子功能材料的设计、合成及其对膜有序相的检测,项目编号:160082102 2015 /7 -2016 / 12; 主持,已结题。


【代表性SCI论文

2022年成果-藻毒素

1. Bingyan Li, Yipeng Liu, Huiyan Chuan, Yong Liu*, Ping Xie*. Excluding interference and detecting Microcystin-LR in the natural lakes and cells based a unique fluorescence method. Water Research2022, 221, 118811. (Nature index IF=14.3, 中科院1TOP)

2. Huixia Zhang, Bingyan Li, Yipeng Liu, Huiyan Chuan, Yong Liu*, Ping Xie**. Immunoassay technology: Research progress in microcystin-LR detection in water samples. Journal of Hazardous Materials, 2022, 424, 127406 (中科院1TOPIF=14.2).

3. Yipeng Liu, Bingyan Li, Huixia Zhang, Yong Liu*, Ping Xie*. Participation of fluorescence technology in the cross-disciplinary detection of microcystins. Coordin. Chem. Rev. 2022, 457, 214416. (中科院1TOPIF=24.8).

4. Huixia Zhang, Zhaomin Wang , Yong Liu * , Ping Xie ** , Exploring the direct effects of microcystin-LR on DNA via using cross-technical means. Ecotoxicology and Environmental Safety, 2022, 241, 113841. (JCR一区TOPIF=7.1)

5. Zhaomin Wang, Congcong Wang, Tianhe Fang, Yong Liu*. Constructing a novel near-infrared fluorescent probe with a large Stokes shift for detection of RNA in the cancer cells. Dyes and Pigments, 2022, 200, 110126 (JCR一区TOPIF=5.1)

6. Yipeng Liu, Bingyan Li, Huixia Zhang, Yong Liu*, Ping Xie. Detection of Microcystin‑LR in the Cells and Natural Lake Water Samples by A Unique Fluorescence‑Based Method. J. Fluresc, 2022, 32, 505-519  (四区,IF=2.2).

第一发明人专利:

1. 一种荧光探针的制备方法和应用,专利号:ZL 2021 1 0598007.8, 授权日期:2022. 05. 03

2. 一种罗丹明类化合物的制备方法和在检测微囊藻毒素中的应用,专利号:ZL 2021 1 1363884.3,授权日期:2022.4.12

3. 一种核糖核酸荧光探针及其制备方法和应用,专利号:ZL 2021 1 1464008. X, 授权日期:2022.4.29 已实现成果转化


2021年成果-藻毒素识别与检测

1. Bingyan Li, Yipeng Liu, Huixia Zhang, Yong Liu*, Ping Xie*. Research progress in the functionalization of microcystin-LR based on interdisciplinary technologies. Coordin. Chem. Rev. 2021, 443, 214041. (被引频次进入学术领域最优秀前0.1%;中科院1TOPIF=24.8).

2016-2020年成果-检测

1. Yong Liu, Jie Niu, Weishan Wang, Yanyan Ma and Weiying Lin, Simultaneous Imaging of Ribonucleic Acid and Hydrogen Sulfide in Living Systems with Distinct Fluorescence Signals Using a Single Fluorescent Probe. Advanced Science, 2018, 51700966 (IF =16.8)

2. Yong Liu, Jie Niu, Weishan Wang and Weiying Lin, Tracking of Mitochondrial Endogenous Ribonucleic Acid in the Cancer Cells and Macrophages Using a Novel Small-Molecular Fluorescent Probe. Anal. Chem., 2019, 91, 1715-1718. (IF =7.0)

3. Yong Liu, Jing Nie, Jie Niu, Weishan Wang and Weiying Lin, An AIE + ESIPT ratiometric fluorescent probe for monitoring sulfur dioxide with distinct ratiometric fluorescence signals in mammalian cells, mouse embryonic fibroblast and zebrafish. J. Mater. Chem. B, 2018, 6, 1973-1983 IF =6.33

4. Minggang Tian, Yong Liu, (共同一作), Yuming Sun, Ruoyao Zhang, Ruiqing Feng, Ge Zhang, Lifang Guo, Xuechen Li, Xiaoqiang Yu, JingZhi Sun, Xiuquan He, A Single Fluorescent Probe Enables Clearly Discriminating and Simultaneously Imaging Liquid-ordered and Liquid-disordered Microdomains in Plasma Membrane of Living Cells, Biomaterials, 2017, 120, 46-56. (IF =12.5)

5. Yong Liu, Fangfang Meng, Longwei He, Xiaoqiang Yu and Weiying LinFluorescence behavior of a unique two-photon fluorescent probe in aggregate and solution states and highly sensitive detection of RNA in water solution and living systems, Chem. Commun., 2016, 52, 8838-8841.(IF=6.2).

6. Yong Liu, Fangfang Meng, Longwei He, Keyin Liu and Weiying Lin*, A dual-site two-photon fluorescent probe for visualizing lysosomes and tracking lysosomal hydrogen sulfide with two different sets of fluorescence signals in the living cells and mouse liver tissues, Chem. Commun., 2016, 52, 7016-7019.(IF=6.2)

7. Yong Liu, Fangfang Meng, Jing Nie, Jie Niu, Xiaoqiang Yu and Weiying Lin. Two-photon fluorescent probe for detecting cell membranal liquid-ordered phase by an aggregate fluorescence method, J. Mater. Chem. B, 2017, 5, 4725-4731. (IF=6.33)

8. Yong Liu, Jie Niu , Weishan Wang , Baoli Dong and Weiying Lin. Unique phenanthrenequinone imidazole-based fluorescent materials with aggregation-induced or two-photon emission. J. Mater. Chem. B, 2017, 5, 7783-7900. ((IF=6.33前封面文章)

9. Yong Liu, Jing Nie, Jie Niu, Fangfang Meng and Weiying Lin, Ratiometric fluorescent probe with AIE property for monitoring endogenous hydrogen peroxide in macrophages and cancer cells, Scientific Reports2017, 17293 (IF=4.38).

10. Yong Liu, Jie Niu, Jing Nie, Fangfang Meng and Weiying Lin. A mitochondria-targetable fluorescent probe with a large Stokes shift for detecting hydrogen peroxide in aqueous solution and living cells. New. J. Chem., 2017, 41, 3320-3325. (IF=3.2).

11. Yong Liu, Fangfang Meng and Weiying Lin, Single fluorescent probe for reversibly detecting copper ions and cysteine in a pure water system, RSC Adv., 2016, 6, 30951–30955.(IF=3.3).

12. Yong Liu, Fangfang Meng, Yonghe Tang, Xiaoqiang Yu and Weiying Lin, A photostable fluorescent probe for rapid monitoring and tracking of a trans-membrane process and mitochondrial fission and fusion dynamics, New J. Chem., 2016, 40, 3726—3731. (IF=3.3).

13. Yong Liu, Weijia Zhang, Yuming Sun, Guofen Song, Fang Miao and Xiaoqiang Yu, Two-photon fluorescence imaging of RNA in nucleoli and cytoplasm in living cells based on low molecular weight probes, Dyes and Pigments, 2014, 103, 191-201. (IF=4.9).

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